Under federal law, EPA is only allowed to register a pesticide to protect food crops if, based on the best available scientific information, exposures from intended uses pose a “reasonable certainty of no harm” to people, including potentially sensitive individuals, such as children and pregnant women. EPA’s pesticide registration process is extremely rigorous, requiring consideration of more than 100 guideline-compliant studies of potential pesticide effects and exposure levels. Safety assessments completed by EPA scientists consider the levels and likelihood of health impacts for farm workers, consumers, and bystanders. The results of these assessments dictate which uses are approved and what labeling precautions must accompany product use. EPA’s registration process also considers potential impacts to fish, birds and other wildlife, and a similarly high level of scrutiny accompanies the Agency’s assessment of environmental safety.

You can provide input into the registration review process for chlorpyrifos.

Changes to federal law in 1988 now further require that, once registered, a pesticide be subject to periodic registration review. These reviews update regulatory assessments with the latest information so that health-based and environmental standards remain protective and exposures are kept to acceptable levels.

Because EPA regulatory evaluations are science-driven and very complicated, they generally take many years to complete. As a consequence, by the time the Agency completes one review of a given pesticide, it may be almost time for the Agency to start work on the next. Such has been the case with chlorpyrifos.

Read more about the evolution of the registration review program.